CLEXANE® is a low molecular weight heparin used to prevent and treat blood clots. In fertility treatments, it is often prescribed to reduce the risk of thrombosis in women undergoing Assisted Reproductive Technology (ART) procedures, such as in vitro fertilisation (IVF).

It may also be used to manage clotting disorders that could interfere with pregnancy outcomes, ensuring optimal blood flow to the uterus and placenta.

The dosage of CLEXANE® depends on the individual’s medical condition and treatment plan. For prophylaxis, a typical dose is 40 mg administered subcutaneously once daily. In cases of clot treatment, higher doses may be prescribed.

Your fertility specialist will determine the exact dosage and duration based on your needs.

CLEXANE® is injected under the skin, usually in the abdomen or thigh, and should not be injected into a muscle.

If you forget to take a dose, administer it as soon as you remember, unless it is close to the time of your next scheduled dose. In that case, skip the missed dose and continue with your regular schedule.

Do not take a double dose to make up for the missed one.

Contact your doctor or pharmacist for advice if you are unsure.

In case of an overdose, seek immediate medical attention. Symptoms may include excessive bleeding or bruising.

Contact the Poisons Information Centre (Australia: 13 11 26) or your doctor or pharmacist for guidance.

Store CLEXANE® below 25°C in its original packaging to protect it from light and moisture. Do not freeze the medication.

Keep it out of reach of children and dispose of used syringes in a designated sharps container.

Common side effects include mild redness, swelling, or bruising at the injection site, which usually resolves quickly. Other possible side effects include nausea, headache, or fatigue.

Rare but serious side effects include excessive bleeding, allergic reactions such as rash or difficulty breathing, and signs of thrombocytopenia (low platelet count).

Contact your doctor immediately if you experience severe symptoms.

CLEXANE® may interact with other medications that affect blood clotting, such as aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), or anticoagulants like warfarin.

Inform your doctor about all medications, supplements, or herbal products you are taking to avoid potential interactions.

How does CLEXANE® help in fertility treatments? CLEXANE® improves blood flow by preventing the formation of blood clots, which can interfere with implantation and pregnancy. It is often prescribed for women with clotting disorders or those at risk of thrombosis during ART procedures.

Can I administer CLEXANE® myself? Yes, if your doctor or nurse has trained you in the proper injection technique. CLEXANE® is injected subcutaneously, usually in the abdomen or thigh. Follow the instructions provided by your healthcare team carefully.

What should I do if I experience side effects? Mild side effects, such as redness or bruising at the injection site, are common and usually temporary. If you experience severe symptoms, such as excessive bleeding or difficulty breathing, contact your doctor immediately. Your healthcare team is here to support you.

Can CLEXANE® be used during pregnancy? CLEXANE® is sometimes prescribed during pregnancy to manage clotting disorders or prevent complications. Your doctor will assess the risks and benefits based on your individual circumstances.

How should I store CLEXANE®? Store CLEXANE® below 25°C in its original packaging, away from light and moisture. Do not freeze the medication, and ensure it is kept out of reach of children.

Ace provides accurate and independent information medically reviewed on prescription medications. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.