Ilumya (tildrakizumab) is a biologic medicine used to treat moderate to severe plaque psoriasis in adults. It works by targeting a specific part of the immune system: it blocks interleukin-23 (IL-23p19), a protein that drives the inflammation responsible for psoriasis plaques.

Ilumya is given as an injection under the skin (subcutaneously) by a healthcare professional or, after training, by yourself.

The standard dosing schedule is:

• Two starter doses given four weeks apart
• Then one injection every 12 weeks (approximately every three months)

Rotate injection sites (thigh, abdomen, or upper arm). Do not inject into areas where skin is red, bruised, or affected by psoriasis.

If you miss an injection, inject as soon as you remember and then restart your 12-weekly schedule from that date. Contact your dermatologist if you are unsure.

An overdose is unlikely in clinical use. If you believe you have injected more than prescribed, contact your doctor.

How Should You Store Ilumya

• Store in a refrigerator between 2°C and 8°C
• Do not freeze
• Keep in the original carton to protect from light
• Once removed from the fridge, it can be stored at room temperature (up to 25°C) for up to 30 days
• Keep out of reach of children

Common side effects:

• Upper respiratory tract infections (such as a cold or sore throat)
• Injection site reactions: mild pain, redness, or bruising

Serious side effects (uncommon):

• Serious infections: tildrakizumab suppresses part of the immune system. Report any fever, chills, cough, or unusual symptoms promptly
• Hypersensitivity reactions: severe allergic reactions are rare but possible. Seek urgent care if you develop throat tightening, rapid heartbeat, or dizziness after injection
  

Before starting Ilumya, you will be screened for tuberculosis and other infections.

• Live vaccines must not be given during treatment
• Other immunosuppressants may increase infection risk when combined

Tell your doctor about all medicines, vitamins, and supplements.

How quickly will my psoriasis improve?

Many people begin to see improvement within 12 to 16 weeks, with continued improvement over the first year of treatment. Clinical studies showed around 60 to 70 percent of patients achieved near-clear or completely clear skin after two years of treatment.

Do I need blood tests while on Ilumya?

Ilumya does not require routine blood monitoring in the same way as some other biologics. Your dermatologist will review your skin response at follow-up visits. Screening for infections such as TB is done before starting.

Ace provides accurate and independent information medically reviewed on prescription medications. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.