REKOVELLE® is used in Assisted Reproductive Technology (ART) treatments, such as in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI), to stimulate the development of multiple follicles in the ovaries.

It is the first recombinant follicle-stimulating hormone (FSH) derived from a human cell line and is administered using an individualised dosing regimen based on a woman’s serum anti-Müllerian hormone (AMH) level and body weight.

The dosage of REKOVELLE® is personalised for each patient. For the first treatment cycle, the daily dose is determined based on the woman’s AMH concentration and body weight.

Treatment typically begins on day 2 or 3 of the menstrual cycle and continues until sufficient follicular development is achieved.

Your fertility specialist will provide specific instructions on the timing and duration of treatment.

If you forget to take REKOVELLE®, contact your fertility clinic or doctor immediately for advice.

Do not administer a double dose to make up for the missed one.

Timing is critical in fertility treatments, so follow your doctor’s instructions closely.

In case of an overdose, seek immediate medical attention. Symptoms may include abdominal discomfort, bloating, or signs of ovarian hyperstimulation.

Contact the Poisons Information Centre (Australia: 13 11 26) or your doctor for guidance.

Store REKOVELLE® in a refrigerator at 2°C to 8°C. Do not freeze the medication. If refrigeration is unavailable, REKOVELLE® can be stored below 25°C for a single period of up to one month.

Keep the medication in its original packaging to protect it from light and moisture, and ensure it is out of reach of children.

Common side effects include mild redness, swelling, or itching at the injection site, which usually resolves quickly. Other possible side effects include headaches, nausea, fatigue, or abdominal discomfort.

Rare but serious side effects include symptoms of Ovarian Hyperstimulation Syndrome (OHSS), such as severe pelvic pain, nausea, vomiting, or sudden weight gain.

Contact your doctor immediately if you experience severe symptoms.

REKOVELLE® may interact with other hormonal medications used during fertility treatments.

Inform your doctor about all medications, supplements, or herbal products you are taking to avoid potential interactions.

Your fertility specialist will guide you on how to safely incorporate REKOVELLE® into your treatment plan.

How does REKOVELLE® work in fertility treatments? REKOVELLE® contains follitropin delta, a recombinant form of follicle-stimulating hormone (FSH). It stimulates the ovaries to develop multiple follicles, increasing the number of eggs available for retrieval during IVF. Its individualised dosing regimen ensures a consistent and evidence-based approach to personalising treatment.

Can I administer REKOVELLE® myself? Yes, REKOVELLE® is designed for self-administration if your doctor or nurse has trained you in the proper injection technique. It is given as a subcutaneous injection, typically in the lower abdomen. Follow the instructions provided by your healthcare team carefully.

What should I do if I experience side effects? Mild side effects, such as redness or swelling at the injection site, are common and usually temporary. If you experience severe symptoms, such as signs of OHSS, contact your doctor immediately. Your healthcare team is here to support you.

Can REKOVELLE® be used during pregnancy? No, REKOVELLE® must not be used during pregnancy. It is specifically designed for use during ovarian stimulation cycles before conception. If you suspect you may be pregnant, inform your doctor immediately.

How should I store REKOVELLE®? Store REKOVELLE® in a refrigerator at 2°C to 8°C. If refrigeration is unavailable, it can be stored below 25°C for up to one month. Always keep the medication in its original packaging to protect it from light and moisture.

Ace provides accurate and independent information medically reviewed on prescription medications. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.